acamprosate Generic Name acamprosate a camp PRO sayt Brand Names Campral What is acamprosate Acamprosate affects chemicals in the brain that may become unbalanced in patients with alcohol dependence Acamprosate is used to help people with alcohol dependence quit drinking alcohol Acamprosate may also be used for purposes other than those listed in this medication guide What is the most important information I should know about acamprosate Acamprosate may impair judgement thinking or motor skills Do not operate hazardous machinery including automobiles until you are reasonably certain that acamprosate does not affect your ability to engage in such activities What should I discuss with my healthcare provider before taking acamprosate Acamprosate has been shown to help alcohol dependent patients to not start drinking again only when it is used as part of a treatment program that includes counseling and support Continue taking acamprosate even if you start drinking again Discuss the fact that you have started drinking again with your doctor if this happens While you are taking acamprosate monitor for symptoms of depression and or suicidal thoughts or actions Contact your healthcare provider if you develop any new or worsening mental health symptoms during treatment with acamprosate Do not stop taking acamprosate without first talking to your healthcare provider Acamprosate is in the FDA pregnancy category C Discuss the risks with your doctor Do not take this medication without first talking to your doctor if you are pregnant or could become pregnant during treatment

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milliliter vial as an isotonic sterile non-pyrogenic solution Each milliliter of the isotonic solution contains 74 megabecquerels 2 millicuries of Gallium Ga 67 on the calibration date as a complex formed from nanograms Gallium chloride Ga 9 milligrams of sodium citrate dihydrate milligrams of sodium chloride and percent benzyl alcohol v v as a preservative The pH is adjusted to between to with hydrochloric acid and or sodium hydroxide solution Gallium Ga 67 with a half-life of hours is cyclotron produced by the proton irradiation of enriched zinc At the time of calibration the drug contains no more than Gallium Ga 66 and no more than Zinc Zn 65 The concentration of each radionuclidic impurity changes with time At expiration the drug contains no more than Gallium Ga 66 and no more than Zinc Zn 65 No carrier has been added Gallium Citrate has the following chemical structure PHYSICAL CHARACTERISTICS Gallium Ga 67 with a physical half-life of hours1 decays by electron capture to stable Zinc Zn 67 Photons that are useful for imaging studies are listed in Table 1 Table 1 Principal Radiation Emission Data1 Radiation Mean Per Disintegration Energy Gamma-2 91 3 Gamma-3 93 3 Gamma-4 184 6 Gamma-5 209 0 Gamma-6 300 2 Gamma-7 393 Kocher D C Radioactive Decay Tables Health and Safety Research Division National Technical Information Service DOE TIC-11026 pg EXTERNAL RADIATION The specific gamma ray constant for Gallium Ga 67 is R mCi-hour at 1 cm The first half-value thickness of lead Pb is cm A range of values for the relative attenuation of the radiation emitted by this radionuclide that results from interposition of various thicknesses of lead is shown in Table 2 For example the use of cm of lead will decrease the radiation exposure by a factor of about 100 Table 2 Radiation Attenuation by Lead Shielding Shield Thickness Pb cm Coefficient of Attenuation 0 41 10-1 10-2 10-3 10-4 To correct for physical decay of this radionuclide the fractions that remain at selected time intervals after the time of calibration are shown in Table 3 Table 3 Physical Decay Chart Gallium Ga 67 Half-Life Hours Calibration Time Hours Fraction Remaining Hours Fraction Remaining 000 72 3d 6 78 12 84 18 90 24 1d 96 4d 30 108 36 120 5d 42 132 48 2d 144 6d 54 156 60 168 7d 66 Gallium - Clinical Pharmacology Gallium Citrate Ga 67 with no carrier added has been found to concentrate in certain viable primary and metastatic tumors as well as focal sites of infection The mechanism of concentration is unknown but investigational studies have shown that Gallium Ga 67 accumulates in lysosomes and is bound to a soluble intracellular protein It has been reported in the scientific literature that following intravenous injection the highest tissue concentration of Gallium Ga 67 - other than tumors and sites of infection - is the renal cortex After the first day the maximum concentration shifts to bone and lymph nodes and after the first week to liver and spleen Gallium Ga 67 is excreted relatively slowly from the body The average whole body retention is 65 percent after seven days with 26 percent having been excreted in the urine and

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information leaflets Do not use Levitra for a condition for which it was not prescribed Do not give Levitra to other people even if they have the same symptoms that you have It may harm them This leaflet summarizes the most important information about Levitra If you would like more information talk with your healthcare provider You can ask your doctor or pharmacist for information about Levitra that is written for health professionals For more information you can also visit www Levitra com or call 1-866-Levitra WHAT ARE THE INGREDIENTS OF Levitra Active Ingredient vardenafil hydrochloride Inactive Ingredients microcrystalline cellulose crospovidone colloidal silicon dioxide magnesium stearate hypromellose polyethylene glycol titanium dioxide yellow ferric oxide and red ferric oxide Norvir ritonavir is a trademark of Abbott Laboratories Crixivan indinavir sulfate is a trademark of Merck Co Inc Invirase or Fortavase saquinavir mesylate is a trademark of Roche Laboratories Inc Reyataz atazanavir sulfate is a trademark of Bristol-Myers Squibb Company Nizoral ketoconazole is a trademark of Johnson Johnson Sporanox itraconazole is a trademark of Johnson Johnson Hytrin terazosin HCl is a trademark of Abbott Laboratories Flomax tamsulosin HCl is a trademark of Yamanouchi Pharmaceutical Co Ltd Cardura doxazosin mesylate is a trademark of Pfizer Inc Minipress prazosin HCl is a trademark of Pfizer Inc Uroxatral alfuzosin HCl is a trademark of Sanofi-Synthelabo Manufactured by Bayer Pharmaceuticals Corporation 400 Morgan Lane West Haven CT 06516 Made in Germany Marketed By GlaxoSmithKline Research Triangle Park NC 27709 Distributed and Marketed By Schering Corporation Kenilworth NJ 07033 Levitra is a registered trademark of Bayer Aktiengesellschaft and is used under license by GlaxoSmithKline and Schering Corporation Bayer Pharmaceuticals Corporation Printed in U S A Levitra vardenafil hydrochloride PRODUCT INFO Product Code

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